Central Pain Modulation

Neuroanatomy and Neuropsychology of Pain

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We have reviewed here the neuroanatomical and neuropsychological literature of the human brain and have proposed the various pain mechanisms that we currently know of. Essentially when tissue is damaged, peripheral nociceptors…

Amygdala Plasticity and Pain

The amygdala is a limbic brain region that plays a key role in emotional processing, neuropsychiatric disorders, and the emotional-affective dimension of pain. Preclinical and clinical studies have identified amygdala hyperactivity as well as impairment of…

Defective Endogenous Pain Modulation in Fibromyalgia: a Meta-Analysis of Temporal Summation and Conditioned Pain Modulation Paradigms


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