CRISPR: Gene Editing in discarded embryos approved in the UK for the study of subfertility and recurrent miscarriages
Introducing the Brave New World of CRISPR Gene Editing: what's in it for rheumatologists and other non-geneticists (that's 99.999% of the guardians of the human genome)?
Plenty. For one, the "corrected" genes can be transfected using a suitable viral vector into patients to treat diseases with clearly-defined genetic causes/predisposition. This may open up a whole new therapeutic modality to prevent or cure many autoimmune, neuromuscular, metabolic diseases and cancers.
Read on and be aware, if not wowed.
Proof-of-concept of CRISPR Gene Editing: treating Duchenne Muscular Dystrophy in mice.
CRISPR/Cas9 (v1.1): this update corrects some errors in the prototype version (it may snip at the wrong places😲)
CRISPR/Cpf1 (v2.0): the science is definitely moving way too fast!