A meta-analysis of six randomized, controlled trials suggests equal efficacy, but patients taking corticosteroids had a lower frequency of indigestion, nausea, and vomiting and a higher frequency of rash.
Objectives To determine the long-term safety and efficacy of allopurinol dose escalation (DE) to…
Evidence-Based Medicine Consult
When lesinurad 400mg was added to febuxostat, significantly more patients achieved target sUA by Month 6 (76.1%; P<0.0001) vs. febuxostat alone (46.8%);…
The US FDA has approved a new fixed-dose and dual-mechanism treatment option for uncontrolled gout.