Mechanistic, Epidemiologic Clues Suggest Possible Link Between Obesity, Inflammation in Rheumatoid Arthritis
Rheumatoid arthritis patients who smoke or are overweight see less symptom improvement with treatment
Fat is bad for RA.
Fat is bad for Psoriasis & Psoriatic Arthritis.
Development of secondary failure to biologics over time in Psoriatic Arthritis and Psoriasis may be due to the development of anti-drug antibodies, especially since the combination with a conventional immunosuppressive DMARD has not been shown to be more efficacious (and therefore unnecessary).
Excessive weight gain is another possible factor, either due to increased volume of drug distribution, or to the pro-inflammatory nature of fat, or both.
The converse, as suggested by this study, is also true.
Fat is bad for Gout.
Fat is bad for your brain, makes you lazy and stupid.