Osteoarthritis

Although osteoarthritis (OA) was formerly considered a non-inflammatory joint disease, it’s now well-appreciated that inflammatory mediators, such as PGE2…
www.the-rheumatologist.org

Osteoarthritis is Inflammatory.

This article is advocating that certain tests for inflammation may help to identify patients at risk of faster cartilage deterioration, so as to treat them more aggressively. It does NOT advocate using targeted (read "expensive" and "potentially hazardous") therapies like anti-TNF/IL1 to treat patients with OA, systemically or intra-articularly, overtly inflammatory or otherwise. Some therapies seem logical theoretically, but don't cut it when subjected to rigorous clinical trials (eg anti-IL6 in Ankylosing Spondylitis, despite a high IL6 signature in inflamed tissue). Perhaps safer and cheaper alternatives with purported anti-inflammatory properties (eg Diacerein, ASU) can be tried till clinical evidence for targeted biologics become available.


Avocado Soybean Unsaponifiables (ASU) for Osteoarthritis

Avocado soybean unsaponifiables (ASU) have been shown in clinical studies to have beneficial effects on osteoarthritis. Avocado soybean unsaponifiables are a…
osteoarthritis.about.com

Management of Osteoarthritis with Avocado/Soybean Unsaponifiables

Osteoarthritis (OA) is a painful and life-altering disease that severely limits the daily activity of millions of Americans, and is one of the most common causes of disability in the world. With...
researchgate.net

Research suggests that ASU may act as a DMOAD (Disease Modifying Osteoarthritis Drug -- the holy grail of systemic OA treatment) through anti-inflammatory means.


Orthopedics Today | <TABLE CELLPADDING="6" CELLSPACING="0" WIDTH="278"…
www.healio.com

OA Knees: Hyaluronic Acid beats Placebo: maybe, maybe not, maybe yes?


Exp Ther Med. 2015 Feb;9(2):493-500. Epub 2014 Dec 15.
www.ncbi.nlm.nih.gov|By Wang F and He X

OA Knees: Hyaluronic Acid as good as Corticosteroids, and lasts longer.


Are you a candidate for PRP? Studies show that if you have osteoarthritis, platelet-rich plasma therapy may be for you. Find more information in this article.
www.arthritis-health.com

OA Knees: Platelet-Rich Plasma beats Placebo.


How does platelet rich plasma compare to hyaluronic acid in treating knee osteoarthritis and chondropathy?
www.medscape.com

OA Knees: PRP as effective (or ineffective) as Hyaluronic Acid.


Knee Arthritis: Steroid Shots May Not Help Long-Term, Ozone Injections Promising

Two studies test out old and new treatments for the debilitating ailment
consumer.healthday.com

OA Knees: Corticosteroids beats Placebo for pain relief, temporarily. How about Ozone?

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