Spondyloarthritis

 
rheumaknowledgy.com

This FREE mobile guide is mighty good!


Tapering treatment in AS

Objective To compare the effectiveness, safety and costs of standard versus individually tailored reduced doses of anti-tumour necrosis factor (TNF) drugs in patients with ankylosing spondylitis (AS) after achieving low-disease activity.
m.ard.bmj.com

This is how I do it. Cost being an overriding constraint, I limit biologic treatment at recommended dosing intervals for the first 3 months as induction of remission. Thereafter, assuming good remission, I increase the dosing interval gradually over the next 3-9 months (depending on individual patient's financial prowess and continuing clinical remission) to eventual twice or 3 times the initial dosing interval, before considering stopping the biologic altogether. If initial response is inadequate, I add NSAID and Sulfasalazine (even if pure axial disease). I will also screen for TB with IGRA, and silent ileiitis with stool calprotectin.


Cosentyx Effective in Psoriatic Arthritis

Secukinumab improved joint scores, skin disease, and radiographic findings
www.medpagetoday.com

No Comments Yet.

Leave a comment