AS Comorbidities

Dr. Jessica A. Walsh

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Ankylosing Spondylitis patients have significant comorbidities. In this 3-year follow-up from initial AS diagnosis, there were significant increased incidences of comorbidities, especially of conditions known to be associated with AS from a pathogenesis basis, such as Uveitis, Inflammatory Bowel Disease, and Osteoporosis.
Lesser known comorbidities include sleep apnoea, asthma, cardiovascular diseases, and cancers.

Current knowledge about the overall and site-specific risk of malignancy associated with ankylosing…

Cancer risk is increased in patients with Ankylosing Spondylitis, especially gastrointestinal and haematological malignancies.

The risk of developing a newly diagnosed depressive disorder persisted for more than 5 years following the AS diagnosis
Ankylosing spondylitis (AS) can cause significant functional impairments and lead to decreased quality of life. Patients with AS have a higher prevalence

A new diagnosis of Ankylosing Spondylitis is associated with sleep disorder, anxiety and depression.
The latter may be reactive to the pain and disability, or a direct effect of systemic inflammation.

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