Knee OA ℞: Viscosupplementation

Predicting Response to Intra-Articular Hyaluronic Acid Treatment in Knee Osteoarthritis

Investigators sought to identify determinants associated with improved response to intra-articular hyaluronic acid treatment in individuals with knee OA.
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Factors predictive of more favourable response to viscosupplementation (less pain, better function, less joint stiffness) are:
1) Younger age group;
2) Larger cartilage volume at the medial compartment;
3) Higher pain level before treatment.