Knee OA: Repair, Regenerate

Comparative effectiveness of dextrose prolotherapy versus control injections and exercise in the management of osteoarthritis pain: a systematic review and meta-analysis

Comparative effectiveness of dextrose prolotherapy versus control injections and exercise in the…
dovepress.com|By Dove Press

To use meta-analysis techniques to evaluate the efficacy and safety of platelet-rich plasma (PRP) injections for the treatment knee of osteoarthritis (OA).
arthroscopyjournal.org

PRP bests Hyaluronic Acid and saline for pain relief and functional improvement in knee OA at 1 year post-injection.

Efficacy of Platelet-Rich Plasma versus Hyaluronic Acid for treatment of Knee Osteoarthritis: A systematic review and meta-analysis

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Knee osteoarthritis is a very common chronic degenerative disease that could impose significant costs to the health system. Although osteoarthritis can affect all joints, knee osteoarthritis is the most common type among adolescents. Non-surgical treatments ...
ncbi.nlm.nih.gov

Cartilage regenerative procedures using the cell-based tissue engineering approach involving mesenchymal stem cells (MSCs) have been receiving increased interest because of their potential for altering the progression of osteoarthritis (OA) by repairing cartilage lesions.The aim of this study was to...
www.sciencedirect.com

The improved clinical outcomes as well as the imaging evidence of structural cartilage reconstitution bode well for mesenchymal stem cell therapy as potentially the treatment of choice for knee OA in future.


First of its kind to be approved, agency says
medpagetoday.com

Matrix-induced Autologous Chondrocyte Implantation (MACI) has been around for quite awhile now, but its recent FDA approval was helped by a comparative study demonstrating its superiority to the traditional microfracture procedure.


Injection of a Wnt inhibitor drug showed promise to ease pain, improve joint function, & slow or reverse cartilage loss in patients with knee…
rheumatology.org

Targeted therapies are finding their way into OA treatment. Wnt inhibition holds promise as a true Disease-modifying OA drug (DMOAD) by increasing cartilage formation, in addition to symptoms relief.

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