Paget Disease

Paget Disease

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Paget disease is a localized disorder of bone remodeling that typically begins with excessive bone resorption followed by an increase in bone formation.…

Intensive bisphosphonate therapy no better than symptomatic therapy in Paget's disease

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In adults with Paget’s disease of bone, intensive treatment with bisphosphonate therapy yielded only…

Targeting Paget’s bone symptoms supported in long-term trial

Long-term intensive bisphosphonate treatment of patients with Paget’s disease of bone continued to show no benefit over symptomatic treatment in a 3-year extension trial of the PRISM study, leading investigators in the trial to recommend that treatment guidelines focus more on managing the condition...

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